6-methylpyrimidin-2(1H)-one hydrochloride
2-HYDROXY-4-METHYLPYRIMIDINE HYDROCHLORIDE
CAS: 5348-51-6
Molecular Formula: C5H7ClN2O
6-methylpyrimidin-2(1H)-one hydrochloride - Names and Identifiers
6-methylpyrimidin-2(1H)-one hydrochloride - Physico-chemical Properties
| Molecular Formula | C5H7ClN2O |
| Molar Mass | 146.57 |
| Melting Point | 243°C (dec.)(lit.) |
| Boling Point | 326.4°C at 760 mmHg |
| Flash Point | 151.2°C |
| Solubility | Water |
| Vapor Presure | 0.000114mmHg at 25°C |
| Appearance | Yellow to or orange powder |
| Color | Green-Yellow |
| BRN | 3691454 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Hygroscopic |
| MDL | MFCD00151347 |
6-methylpyrimidin-2(1H)-one hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
6-methylpyrimidin-2(1H)-one hydrochloride - Introduction
HYDROCHLORIDE, chemical formula is C5H7N2O · HCl, it is an organic compound, white crystalline powder solid.
Nature:
1. Appearance: white crystalline powder.
2. solubility: soluble in water and alcohol solvents, slightly soluble in ether.
3. melting point: about 187-189 ℃.
4. chemical properties: the compound is a basic substance, can react with acid to generate the corresponding salt.
Use:
The HYDROCHLORIDE has a wide range of applications in chemical and biological research.
1. chemical reagents: commonly used in the synthesis of deoxynucleotides and nucleic acid related experiments.
2. Drug synthesis: As an important intermediate, it can be used to synthesize a variety of drugs, such as antiviral drugs and anti-tumor drugs.
Preparation Method:
The preparation method of HYDROCHLORIDE is relatively simple and can generally be carried out through the following steps:
1.4-methyl pyrimidine dissolved in dilute sulfuric acid;
2. Add excess sodium hydroxide solution to make the pH value of the solution alkaline;
3. Filtration to obtain a precipitate;
4. The precipitate reacts with hydrochloric acid to generate hydrochloride of 2-hydroxy-4-methylpyrimidine.
Safety Information:
1. No special danger to HYDROCHLORIDE, but still need to follow the laboratory safety procedures.
2. During use and storage, contact with strong oxidants should be avoided to prevent chemical reactions.
3. use should wear appropriate personal protective equipment, such as gloves and safety glasses.
4. If you touch your skin or eyes by accident, rinse immediately with plenty of water and seek medical help.
Nature:
1. Appearance: white crystalline powder.
2. solubility: soluble in water and alcohol solvents, slightly soluble in ether.
3. melting point: about 187-189 ℃.
4. chemical properties: the compound is a basic substance, can react with acid to generate the corresponding salt.
Use:
The HYDROCHLORIDE has a wide range of applications in chemical and biological research.
1. chemical reagents: commonly used in the synthesis of deoxynucleotides and nucleic acid related experiments.
2. Drug synthesis: As an important intermediate, it can be used to synthesize a variety of drugs, such as antiviral drugs and anti-tumor drugs.
Preparation Method:
The preparation method of HYDROCHLORIDE is relatively simple and can generally be carried out through the following steps:
1.4-methyl pyrimidine dissolved in dilute sulfuric acid;
2. Add excess sodium hydroxide solution to make the pH value of the solution alkaline;
3. Filtration to obtain a precipitate;
4. The precipitate reacts with hydrochloric acid to generate hydrochloride of 2-hydroxy-4-methylpyrimidine.
Safety Information:
1. No special danger to HYDROCHLORIDE, but still need to follow the laboratory safety procedures.
2. During use and storage, contact with strong oxidants should be avoided to prevent chemical reactions.
3. use should wear appropriate personal protective equipment, such as gloves and safety glasses.
4. If you touch your skin or eyes by accident, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:58
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CAS: 5348-51-6
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Product Name: 2-Hydroxy-4-Methylpyrimidine Hydro- Chloride Visit Supplier Webpage Request for quotation
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